Programmable multi-modal dynamic contrast enhancement (DCE) blood flow perfusion phantom simulates extracorporeal blood flow and two-chamber contrast blood flow by controlling blood flow changes based on step function or typical clinical arterial input function (AIF) input pressure Kinetics This innovative phantom can generate a wide range of predictable, reproducible and quantifiable time-concentration curves (TCC). These curves generate a wide range of real input and output functions that simulate clinically relevant perfusion TCC. The phantom generation has The ability of the DCE quality assurance protocol for real blood flow provides an excellent model for the verification of perfusion and kinetic modeling, and enables DCE imaging to be used as a quantitative imaging tool for scanners in contrast imaging mode, or Compatible with CT MRI and PET modes, and contrast imaging mode. The standard DCE phantom prediction software accurately and repeatably predicts the TCC that will be presented when the phantom is scanned to obtain the established input parameter selection and can generate a wide range of physiologically relevant enhancements. Curve, the user can define the required TCC and calculate the input parameters required for the model. The easy-to-use DCE phantom prediction software allows users to select the following: CT MR or PET imaging method Maximum time injection parameter output flow and perfusion pump flow.

Applications

CT

-Perfusion/DCE CT

-Image noise and partial volume effect quantification

-CT digital linearity and sensitivity

MR

-Based on the size and phase of DCE-MR

-Arterial Spin Labeling (ASL)

Dynamic PET

Compare various single-mode scanners

Comparison of multi-modal scanners

Kinetic model verification

Assess the interaction between dynamic contrast blood flow and dynamic image acquisition

Features

Product advantages

CT

-Perfusion/DCE CT

-Image noise and partial volume effect quantification

-CT digital linearity and sensitivity

MR

-Based on the size and phase of DCE-MR

-Arterial Spin Labeling (ASL)

Dynamic PET

Compare various single-mode scanners

Comparison of multi-modal scanners

Kinetic model verification

Assess the interaction between dynamic contrast blood flow and dynamic image acquisition

Multimodal DCE blood flow phantom

Compatible with X-ray computed tomography (CT), magnetic resonance (MR) and positron emission tomography (PET) imaging modes

Create a wide range of physiologically relevant time-concentration curves under physiological and steady-state flow rates (TCCs), similar to those observed in clinical perfusion CT/MR

Accurate and highly repeatable comparative measurement in dynamic settings

Predictable and reproducible time enhancement curve

Perform CT digital linearity and sensitivity test, convert CT digital enhancement into concentration DCE prediction software

The easy-to-use automated DCE phantom prediction software for CT MRI and PET imaging produces a wide range of clinically relevant and reproducible contrast enhancement curves

Model data is easily exported to MATLAB data file or Excel spreadsheet

Provide baseline comparison calibration curve.

Provide comparison of real imaging modes of CT, MRI and PET scanners,

Provides the gold standard across multiple imaging platforms

Develop dynamic collection protocol to improve dose efficiency

Improve quantitative contrast enhanced imaging and quantify scanner variability

Use the time decay curve generated by phantom

Evaluate the sensitivity of a single scanner

For different CT scanners and acquisition protocols

Perform a basic ROI sensitivity analysis test

Further verify the parameters of the kinetic model

Detailed Specifications

Torso Shell, made of acrylic and sealed

Fluid Mass Exchange Cylinder which embodies a spiraling interior perforated distribution tube with input and output tubes

Injection Port complete with backflow prevention, syringe port and required fittings for typical clinical IV administration.

Needle Valves Control (2)

-4” (6.35 mm) ID carbon stecl for CT/PET

-44" (6.35 mm) ID polypropylene for MRIT

urbine Flow Meters (2):

-50-500 ml/min range (1/8" ID or 3.175 mm)

Turbine Flow Meter Power Supplies (2)

3-Way Ball Diverter Valve:

14" ID, brassTubing-14 feet (4.2672 m), %" (6.35 mm) ID high pressure clear PVO tubing, food grade

-3.70 feet (113 cm), 1/8" (3.175 mm) ID clear PVC tubing, chemical resistant

-5 feet, (152.40 cm), 4" (6.35 mm) high temperature silicone soft rubber tubing.