In Vivo Two-Photon Endoscopy System-Worldwide Technology (S.H)

In Vivo Two-Photon Endoscopy System

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In Vivo Two-Photon Endoscopy System
description：	InSplorer is a turnkey multimodal nonlinear endoscopic imaging system that supports various imaging modalities including two-photon (2P), three-photon (3P) fluorescence imaging, second and third harmonic generation (SHG, THG), and coherent anti-Stokes Ram

System Overview
InSplorer is a turnkey multimodal nonlinear endoscopic imaging system that supports various imaging modalities including two-photon (2P), three-photon (3P) fluorescence imaging, second and third harmonic generation (SHG, THG), and coherent anti-Stokes Raman scattering (CARS). The system operates through connection with an independent control cabinet, which houses the laser, opto-electronic modules, and dedicated image acquisition and processing software.

Available Laser Sources:
Pulsed femtosecond or picosecond lasers
Optional integrated laser module for a fully stand-alone system
If the user already has a laser, it can be connected to the InSplorer system using the FemtoGuide delivery fiber (or any FC/PC connector-compatible fiber)

Software Platform – ImageVivo:
Custom software dedicated to endoscope probe calibration and image acquisition
Multi-Modal Endoscope Probe Performance
Tissue/Cell Imaging Applications:
Tissue and cell imaging: High-resolution imaging of collagen, lipids, NADH, and NADP
Neuroscience research: Suitable for deep brain structure imaging using 2P and 3P techniques
Label-free skin imaging: Acquire structural information without the need for staining
Supported Imaging Modalities (Fluorescence and Label-Free):
Two-Photon Fluorescence (2P)
Three-Photon Fluorescence (3P)
Second Harmonic Generation (SHG)
Third Harmonic Generation (THG)
Coherent Anti-Stokes Raman Scattering (CARS)
Imaging Performance:
Frame rate: up to 10 Hz (*limited by the scanner’s resonant frequency)
Field of view (FOV): up to 600 µm *
Lateral resolution (XY) and working distance (WD):

Axial resolution: 15 µm (2P); 5 µm (3P)
Numerical aperture (NA): 0.7 (GRIN-MO); 0.45 (4L-MO)
Supports broadband, low-dispersion delivery fibers
Application – Tissue Imaging Examples

Application – Multimodal Imaging Examples

Application – Multimodal Imaging Examples

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In Vivo Two-Photon Endoscopy System

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