Image Guided Laser Microtome-Worldwide Technology (S.H)

Image Guided Laser Microtome

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Image Guided Laser Microtome
description：	The laser microtome TissueSurgeon is a multipurpose sectioning instrument, which enables precise and contact free cutting of biological samples and a broad range of (bio-) materials. Based on femtosecond laser technology, it can be used for sectioning, st

Summarize
The laser microtome TissueSurgeon is a multipurpose sectioning instrument, which enables precise and contact free cutting of biological samples and a broad range of (bio-) materials. Based on femtosecond laser technology, it can be used for sectioning, structuring or gentle extraction of samples and materials in 2D and 3D for analysis. Fundamental limits of mechanical tissue preparation can be overcome for cutting of hard tissue, implanted tissue or difficult to cut materials, such as adipose tissue, ceramic scaffolds or polymers. The TissueSurgeon surmounts major limitations of common methods like mechanical microtomy, ground sectioning or laser-microdissection (LMD). In addition, in combination with imaging modules the TissueSurgeon does not only allow for guided twodimensional sectioning but also for three-dimensional cutting. This provides great flexibility and enables novel approaches.

Advantage
Nearly serial sections of non-decalcified hard tissue (e.g. bone) with minimal loss of material
Histology of hard and soft tissue, even delicate samples (e. g. cochlea, adipose tissue)
Sectioning of biomaterials for tissue engineering (e.g. scaffolds, teflon, hydrogels)
Implant-tissue interface histology (e.g. dental screws, cardiovascular stents, scaffolds)
Contact free laser cutting of tissue avoids artefacts like compressions, scratches or cracks
Gentle isolation of site-specific samples by image guided 3D-sectioning (e. g. along the implant-tissue interface of dental screws) for biochemical analysis
3D-microstructuring of tissues, matrices and materials
Application
Orthopedics/ Trauma and Osteology
Oro-facial and Dental Medicine
Oto-laryngealogy and Audiology
Cardiology and Cardiovascular Research
Regenerative Medicine and Tissue Engineering
Soft tissue difficult to cut
Preclinical studies from small to large animal models

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Image Guided Laser Microtome

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