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Laser microdissection
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Single cell isolation combined with laser microdissection
(LMD) is a precision sample preparation technique. In many research fields, LMD is the basic premise for obtaining clear starting materials for many downstream experiments.
The most accurate and gentle laser microcutting
To ensure meaningful data from specific cells, precisely cut cell clusters, individual cells or subcellular compartments, MMI CellCut combines the most precise cutting performance to ensure excellent sample integrity and the highest flexibility and ease of use. Take your research to the next level!
Tumor heterogeneity
Understanding tumor heterogeneity is one of the main goals of cancer research and oncology. Tumor tissue is a complex and heterogeneous structure composed of different types of cells, all of which contribute to tumor quality and tumor microenvironment.
Laser microdissection with MMI CellCut is the perfect tool for excising individual tumor cells to study their mutation burden. Different staining techniques can help identify tumor cells as well as different subclones within heterogeneous tumor masses. The technique can be applied to any cancer type that exhibits tissue heterogeneity, such as breast, lung, or prostate cancer.
From slide to tube: MMI CapLift technology
The unique CapLift technology automatically transfers uncontaminated targets from the entire microscope slide into microtubules. Therefore, your sample can be used immediately for subsequent "under.
Travel "molecular biology analysis.
Always check your cutting efficiency
In addition, the MMI CapLift technology allows for full visual inspection of samples during and after separation. The orientation of the cells will remain the same, which allows you to easily verify the presence of anatomic regions in the separation cap. In addition, you can hold the sample in place during the cutting process to prevent individual cells from bouncing off. You will like this work
Yes, because it can be used for rare cell research and your reviewers will love it too!
Living cell
The isolation and isolation of living cells is a necessary prerequisite to obtain homogeneous cell cultures. However, the procedure of generating homogeneous cell cultures from selected cells is very laborious and difficult to perform under physiological and sterile conditions. As a result, cells are less likely to grow and divide into new cells, and the risk of contamination makes these processes unreliable.
MMI CellCut can easily and gently cut living cells to obtain a homogeneous population of living cells. In contrast to systems that use an upright microscope, the MMI laser comes from below. As a result, you can dissect living cells without removing the medium to ensure the highest cellular integrity for meaningful omics applications and recultures.
Advanced single cell isolation
Laser microcutting with MMI CellCut provides a fully auditable and automatically documented workflow. With the intuitive and flexible MMI CellTools analysis software, you can simply select, cut, collect and examine samples. After that, your sample is ready for downstream processing.
Clean cutting
The sample is fixed between the glass sheet and the carrier film, and the entire cutting process is non-contact, effectively preventing contamination.
Detailed Specifications