BRILLOUIN OPTICAL SCANNER SYSTEM BOSS-Worldwide Technology (S.H)

BRILLOUIN OPTICAL SCANNER SYSTEM BOSS

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BRILLOUIN OPTICAL SCANNER SYSTEM BOSS
description：	Biomechanical imaging with the Brillouin Optical Scanner System, or BOSS, will address a large range of ophthalmic indications. BOSS is a non-contact, confocal, high-resolution optical scanning platform targeted at identifying the biomechanical properties

Brillouin Optical Scanning System — BOSS
Product Overview
Biomechanical imaging using the Brillouin Optical Scanning System (BOSS) addresses a wide range of ophthalmic indications. BOSS is a non-contact, confocal, high-resolution optical scanning platform designed to identify the biomechanical properties of ocular tissues such as the cornea or lens, enabling the generation of spatially resolved profiles of in vivo tissue stiffness.
Working Principle
BOSS analyzes tissue reverberation using light energy to determine its elasticity through the following method:

Data from the maps can help clinicians identify abnormalities or weaknesses—critical information for surgeons aiming to provide the best possible care for patients.
Brillouin Principle
Brillouin spectroscopy leverages optical principles to detect the speed of sound within living tissues, allowing the determination and visualization of their 3D and real-time viscoelastic properties. “Inelastic scattering” was first detected in 1922 by Isamon Brillouin, but only recently has the BOSS Brillouin scanner made its commercialization technically feasible.
When the low-power, narrowband near-infrared laser from BOSS is focused into the tissue, interactions between light and inherent acoustic waves within the local tissue volume generate Brillouin scattering. A confocal spectrometer then analyzes the Doppler Brillouin frequency shift, which is directly related to the elastic modulus at that point. This enables mapping in all three dimensions and the generation of stiffness maps for the cornea, lens, and other ocular structures.
Product Advantages
The biomechanical imaging of the Brillouin IVF system enables quantitative measurement of the biomechanics (viscosity and elasticity/stiffness) of living tissues and cells without any physical contact. This non-contact, confocal, high-resolution scanning platform identifies biomechanical characteristics of structural differences in tissues, allowing users to construct spatially resolved profiles of in vivo tissue stiffness—significantly improving applications such as embryo and oocyte selection.
Application Areas
In vivo, localized measurement of Young’s modulus; direct measurement of the stress-strain relationship in ocular tissues; impact on the eye’s refractive performance from the cornea to the retina—from the eye’s surface through to the retina-sensory system.

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