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Tilt High Resolution Light Sheet Imaging System

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  • Tilt High Resolution Light Sheet Imaging System

    description: The Tilt from Mizar Imaging is a modular light sheet illumination system designed for high-resolution imaging. Mounting to most inverted microscopes, the Tilt enables light sheet imaging to be easily added to an existing or new microscope system.
    Summarize
    The Tilt from Mizar Imaging is a modular light sheet illumination system designed for high-resolution imaging. Mounting to most inverted microscopes, the Tilt enables light sheet imaging to be easily added to an existing or new microscope system.
    The Tilt brings Lateral Interference Tilted Excitation (LITE) microscopy (Fadero, et al., 2018) to the market. LITE microscopy eliminates the steric interference between illumination and detection objectives found in conventional light sheet illumination methods. Thus making it compatible with any detection objective, including high NA objectives (1.4 and greater). The Tilt system includes the LITE illumination module and an X,Y, PiezoZ substage, enabling high-speed, high-resolution, 3D light sheet imaging on a standard inverted microscope.
    Advantage
    Minimal photobleaching and phototoxicity Compatible with a wide range of sample types Adapts to most inverted microscopes Does not interfere with transmitted light and other modes of illumination Designed to work with both high and low NA objectives No image reconstruction needed Simple to use Accepts any single mode laser Compatible with any camera.
    Application
    Developmental biology
    C. elegans D. melanogaster D. rerio X. laevis
    Embryogenesis
    Intracellular dynamics
    Imaging of photosensitive cells and tissues
    Plant imaging
    Long term, live cell imaging
    Detailed Specifications