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SUPER SESI

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SUPER SESI
description：	Basic introduction: SUPER SESI is a high efficiency Secondary Electrospray Ionization ( source optimized for the analysis of volatile and semi volatile organic compounds in real time。 SUPER SESI is compatible with high resolution Mass Spectrometers Exact

How it works
A nano-electrospray produces charging agents at highconcentration.
Charge is transferred from protonated clusters to thevapors and nano-aerosols via Charge Transfer Reactions and Field ChargingEffects.
Charged vapors and nano-aerosols are desolvated, transferredinto the vacuum side of the MS, and analyzed.
SSX provides biologically relevant data inreal-time. We achieve this by measuring large molecules, which are morespecific from a biological standpoint. More specific biomarkers are morerelevant for clinical diagnosis. But this molecules tend to have verylow-volatility and low concentration, so detecting them could be challenging.

Advantages
WhySESI is ideal for large vapor molecules and nano-aerosols:
Becauseionizing at atmospheric pressure improves limits of detection:
Turbulentlosses and condensation losses are eliminated, which means more molecules reachthe ionization area. Since molecules are ionized before they reach theadiabatic expansion and cooling, region process (instead of at the entrance ofthe ionizer as it happens in low-pressure operating systems), ions are heatedby electric fields and focused.
Theionization reaction is much faster, which means better ionization efficiency.The velocity scales with the concentration of the vapors and the concentrationof the charging ions, both of them go with the pressure in the ionizer. At roompressure (10^3 mBar), the velocity of the charge reaction is 10^6 times higherthan at 1 mBar.
Highperformance Electrospray - MS systems are optimized to transfer and desolvateheavy ions from atmospheric pressure into their vacuum side. This challengingtechnical problem is already solved by currently available commercial MSsystems. SSX just rides very powerful horses!
Theionization efficiency of nano-electrospray is extremely high because theconcentration of charging agents near the nano-jet is extremely high
Lowvolatility species tend to be more specific from a biological standpoint,,but they are often very diluted because they have a low vapor pressure. SESIionizes them with extreme efficiently
Becausethe nano-electrospray provides very clean spectra:
in-sourceion fragmentation and oxidation is very low because there are no high energyions present at any point in the ionizer. Compared with other sources usingplasma as a source of charging ions, SESI ions are formed from evaporatingnano-droplets. The result is a lot simpler spectra, which are easier tointerpret. This is particularly important for untargeted studies, like biomarkerdiscovery.
Application：
Breath analysis: Breath is the onlybio-fluid that is continuously available in large amounts, and it carries manyparticles, such as endogenous or exogenous metabolites, Volatile OrganicCompounds (VOCs), proteins, viral particles, drug metabolites…
Volatilomics: The detection and study ofVolatile Organic Compounds (VOCs) emitted or present in different systems canreveal significant information about their state. With SUPER SESI-X , you candetect these VOCs in real-time in a non invasive way, which can be veryrelevant in many fields.
Food and aroma: Food contamination, Foodfraud, Traceability, Aroma profiling, flavor quantitative analysis anddevelopment.
Microbiology: Monitor cell culturegrowth, target metabolic pathways with isotopic labels, study the response tospecific conditions.
Plants: Monitor the metabolism ofplants, and their metabolic response to different stimuli.
Ambient: Trace detection, organiccontaminants in clean-rooms, explosives, CBRN, pesticides, and environmentalmonitoring.

Detailed Specifications

General Data：
Power: 220-240 V, 50-60 Hz, 250VA
Dimensions: 207x200x291 mm
Weight: 10Kg
Max. temperature of sample line: 180ºC
Max. temperature of ionization chamber: 130ºC
Protection level: IP20

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