ANANDA product introduction

• Best-in-class high-throughput in vitro platform for neuronal network formation and screening

• 3000 neurons and 120 single axon replicates per sample

• Generate high-quality, reproducible results faster

• Compatible with industrial automation solutions such as liquid handlers and flat panel imagers

• Improve standardization, efficiency, reproducibility and reliability

• Reduce and replace animal experiments with more human-relevant models

Product advantages

Improved clinical relevance

Neuronal network organization resembles human physiology

standardization

All neural networks are grown, tested and analyzed under standardized conditions

reproducibility

Parallel axon organization patterns for easy comparison within and between tests

easy to analyze

Clear neuronal organization lowers barriers to analysis of complex neuronal networks

lower cost

Requires fewer cells, fewer reagents, fewer animals and less time

Application field

What you can do with NeuroHTS™ Preclinical testing: 1. Viral transport and MoA analysis 2. Drug screening test 3. Neurotoxicity assay

Human disease modeling: 1. Parkinson's disease 2. Spinal cord injury 3. Multiple sclerosis 4. Alzheimer's disease 5. Amyotrophic lateral sclerosis

Additional applications

• Receptor-ligand interactions

• Synapse formation

• Network formation

• Microglia formation

• Neuronal cell-to-cell communication with other cell types (eg microglia, astrocytes, etc.)

Technical parameter

• Virus transport in neurons (eg herpes virus, rabies virus, etc.)

• Axon growth

• Axonal degeneration and regeneration

• Axonal transport

• Reproduce in vivo cellular organization with 3 µm accuracy

• 1 mm + axon length

• Achieve >30 days of neuronal survival

• Save 90% on cells and reagents

• 60 times faster axon growth

• 50% faster results imaging

• Replace/reduce reliance on animal models

• Improve reproducibility and reliability of results through consistent, uniform culture of cell organization

Detailed Specifications